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S)-AHPC-CO-PEG4-propargyl Synonyms CAS Number 2267282-21-1 Related CAS Molecular Formula C34H48N4O8S Molecular Weight 672
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including high photostability
Product Name dCeMM1 Synonyms CAS Number 118719-16-7 Related CAS Molecular Formula C14H13BrN2O3S Molecular Weight 369
Mal-Propionyl-PEG4-Val-Cit-PAB(m-PEG8)-MMAE bronic ester S)-AHPC-CO-PEG4-propargyl Synonyms CAS Number 2267282-21-1SOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG4 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly
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